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Flea Control and Your Dog

Flea control is a vital part of pet ownership. You, your family and your pets can be affected by these tiny, blood-sucking pests. In fact, fleas have a role in the transmission of several canine and human disease-causing organisms and other parasites — and they're found throughout the country.

Trifexis® (spinosad + milbemycin oxime) protects your dog against fleas. Trifexis provides fast relief. It starts killing fleas within 30 minutes and proved 100% effective within four hours in a controlled laboratory study.

Trifexis offers these additional benefits:

  • Lasts a full month
  • Kills fleas before they can lay eggs
  • Can't be rubbed, washed or shaken off

Learn more about Trifexis and how it can protect your dog from fleas and other dangerous parasites.

The following 14-minute video provides an overview about fleas by Dr. Michael Dryden, Professor of Veterinary Parasitology at Kansas State University and leading expert in fleas. Or you can use the links on the left to explore pages with information about fleas, the flea lifecycle, and how to control fleas on your pet and in your home.

“The Dirt on Fleas: An Educational Video”

Michael Dryden, DVM MS, PhD

Michael Dryden, DVM, uses his 20+ years of experience to explain how to relieve pet discomfort, eliminate all flea life stages, and prevent future infestations.

Video won't play? Click here to download the MP4.

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Available by prescription
from your veterinarian.

DVM and Staff Site

Important Safety Information

Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis chewable tablets.

Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy.

The most common adverse reactions reported were vomiting, depression/lethargy, itching, decreased appetite, and diarrhea. To ensure heartworm prevention, observe your dog for one hour after administration. If vomiting occurs within an hour of administration, redose with another full dose. Puppies less than 14 weeks of age may experience a higher rate of vomiting.

View full product label for complete safety information.

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