Innovative products helping pets live longer, healthier, higher-quality lives.

Trifexis logo

 

Trifexis® (spinosad + milbemycin oxime) is the monthly, beef-flavored tablet that kills fleas and prevents flea infestations, prevents heartworm disease, and treats and controls adult hookworm*, roundworm and whipworm infections in dogs. Trifexis is safe for use in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater.

*Ancylostoma caninum 

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Important Safety Information for Trifexis

Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis chewable tablets.

Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy.

The most common adverse reactions reported are vomiting, depression/lethargy, itching, decreased appetite, and diarrhea. To ensure heartworm prevention, observe your dog for one hour after administration. If vomiting occurs within an hour of administration, redose with another full dose. Puppies less than 14 weeks of age may experience a higher rate of vomiting. Like all medications, keep Trifexis out of reach of children.

Visit our safety facts page or view full product label for complete safety information.


Interceptor Plus logo

 

Interceptor® Plus (milbemycin oxime/praziquantel) is the chewable tablet flavored with real chicken that prevents heartworm disease, and treats and controls adult hookworm, roundworm, whipworm and tapeworm infections in dogs.* Interceptor Plus is safe for use in dogs and puppies 6 weeks of age or older and 2 pounds of body weight or greater.

*Heartworm (Dirofilaria immitis), hookworm (Ancylostoma caninum), roundworm (Toxocara canis, Toxascaris leonina), whipworm (Trichuris vulpis), tapeworm (Taenia pisiformis, Echinococcus multilocularis, Echinococcus granulosus)

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Important Safety Information for Interceptor Plus

Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Interceptor Plus, dogs should be tested for existing heartworm infections. The safety of Interceptor Plus has not been evaluated in dogs used for breeding or in lactating females. The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel, the active ingredients in Interceptor Plus: vomiting, diarrhea, depression/lethargy, incoordination, decreased appetite, convulsions, weakness, and salivation. See Interceptor Plus label for complete safety information.


Interceptor logo

 

Interceptor® (milbemycin oxime) is a once-a-month tablet that prevents heartworm disease, controls adult hookworms, and removes and controls adult roundworm and whipworm infections in dogs.* And in cats, one monthly tablet prevents heartworm disease and removes adult roundworms and hookworms.** Interceptor is safe for use in dogs and puppies 4 weeks of age or older and 2 pounds of body weight or greater, and for cats and kittens 6 weeks of age or older and 1.5 pounds of body weight or greater.

*Heartworm (Dirofilaria immitis), hookworm (Ancylostoma caninum), roundworm (Toxocara canis, Toxascaris leonina), whipworm (Trichuris vulpis)

**Heartworm (Dirofilaria immitis), hookworm (Ancylostoma tubaeforme), roundworm (Toxocara cati)

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Important Safety Information for Interceptor

Dogs and cats should be tested for heartworm prior to use. In a small percentage of treated dogs, digestive and neurologic side effects may occur. In cats, safety studies at up to 10 times the label dose did not detect any adverse drug reactions. See Interceptor label for complete safety information.


Comfortis logo

 

Comfortis® (spinosad) starts killing fleas in 30 minutes, provides a full month of protection and eliminates flea infestations in just 3 months when given monthly to cats or dogs. Comfortis is safe for use in dogs and puppies 14 weeks of age or older and 3.3 lbs of body weight or greater, and cats and kittens 14 weeks of age or older and 2 pounds of body weight or greater.

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Important Safety Information for Comfortis

For cats: The most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin.

The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated. See Comfortis label for complete safety information.

For dogs: The most common adverse reaction reported is vomiting. Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation, and seizures.

Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions.

Use with caution in breeding females and dogs with pre-existing epilepsy. The safe use of Comfortis in breeding males has not been evaluated. See Comfortis label for complete safety information.


Cheristin logo

 

Cheristin® for cats (spinetoram) is topical flea control that killed 98-100% of fleas in 12 hours in a controlled laboratory study and lasts a full month.1,2 It’s fast, effective, long-lasting protection for the cat you love. Cheristin is approved for use in kittens 8 weeks of age and older and 1.8 pounds of body weight or greater.

Learn more about Cheristin for cats


Parastar Plus logo

 

Parastar® Plus for Dogs (fipronil/cyphenothrin) is double-action tick and flea control that is quick acting (starts killing fleas and ticks in 5 minutes) and lasts for a full month.3 Parastar Plus is approved for use in dogs and puppies 12 weeks of age or older and 4 pounds of body weight or greater.

Learn more about Parastar Plus for dogs


Parastar logo

 

Parastar® for Dogs (fipronil) is powerful tick and flea control that kills ticks, including those that may transmit Lyme disease, fleas, chewing lice and mites that may cause sarcoptic mange. Parastar is approved for use in dogs and puppies 8 weeks of age or older and 4 pounds of body weight or greater.

Learn more about Parastar for dogs


EasySpot logo

 

EasySpot® for Cats is a topical flea and tick control for your cat. Applied as a single spot, EasySpot results in fast-acting and long-lasting control of fleas, ticks and chewing lice for 30 days. EasySpot is approved for use on cats and kittens 8 weeks of age and older and 1.5 pounds of body weight or greater.

Trifexis, Interceptor, Comfortis, Cheristin, Parastar, EasySpot, Elanco, and the diagonal bar are trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.