Trifexis Spinosad Milbemycin Oxime

Trifexis® (spinosad + milbemycin oxime) combines two powerful active ingredients that protect your dog safely and effectively against three types of dangerous parasites.

An Eli Lilly scientist discovered spinosad on a beach vacation in the Caribbean. Now, it’s the active ingredient in Trifexis that:

  • Starts killing fleas in just 30 minutes—before they can lay eggs
  • Killed 100% of fleas in 4 hours in a controlled laboratory study in dogs
  • Provides an entire month of full flea protection

Milbemycin oxime is the other active ingredient in Trifexis. It’s a safe way to prevent heartworm disease as well as treat and control adult hookworm*, roundworm and whipworm infections in dogs.

*A. caninum