Veterinarians and owners recommend Trifexis

January 09, 2018 Category: Trifexis

When it comes to your dog’s health, you trust your veterinarian because he’s a trained expert who spent a lifetime learning how to care for animals. So, when your veterinarian prescribes Trifexis® (spinosad + milbemycin oxime) for your dog, it’s because he knows that it works.

Trifexis is the #1-prescribed combo parasite protection for dogs1, so it’s no surprise that many veterinarians trust Trifexis enough to give it to their own dogs. Veterinarians understand the science behind the product and know—first-hand—how easy and effective it is to give Trifexis to their dogs. That’s why they recommend it for so many of their clients.

Veterinarians also hear from plenty of satisfied dog owners who love Trifexis. In fact, more owners would recommend Trifexis to a family member or friend than any other brand.2 While your friends and family members may not know the science behind Trifexis, they know that it works, and that knowledge should give you peace of mind when it comes to protecting your dog.

Ask your veterinarian about Trifexis. It’s the monthly, beef-flavored tablet that kills fleas and prevents flea infestations, prevents heartworm disease, and treats and controls adult hookworm (A. caninum), roundworm and whipworm infections. It’s approved for use in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater.


The use of ivermectin at higher than FDA-approved doses at the same time as Trifexis can result in serious side effects. Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy.

The most common adverse reactions reported are vomiting, depression/lethargy, itching, decreased appetite, and diarrhea. To ensure heartworm prevention, observe your dog for one hour after administration. If vomiting occurs within an hour of administration, redose with another full dose. Puppies less than 14 weeks of age may experience a higher rate of vomiting. Like all medications, keep Trifexis out of reach of children.

View full product label for complete safety information.